Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486405 | 0.85 | — | — | |
| SCHEMBL4060558 | 0.84 | HPGD (0.30) | HPGD | |
| SCHEMBL28757192 | 0.82 | — | — | |
| SCHEMBL29929218 | 0.82 | TP53 (0.41) | — | |
| SCHEMBL638667 | 0.82 | TP53 (0.41) | — | |
| SCHEMBL29094042 | 0.80 | ACHE (0.31) | — | |
| SCHEMBL27701066 | 0.80 | TP53 (0.39) | — | |
| SCHEMBL9489355 | 0.79 | CES2 (0.39) | HPGD | |
| SCHEMBL14262852 | 0.77 | CA3 (0.30) | NISCH | |
| SCHEMBL23804443 | 0.76 | VCAM1 (0.38) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238611-A | Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine | SPOFA, UNITED PHARMACEUTICAL WORKS (CS) | 1980-12-09 | — | — | US | disclosed |