Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489400 | 0.86 | CYP2C9 (0.44) | CYP2C9MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11487043 | 0.81 | ALDH1A1 (0.38) | DRD2OPRM1DRD3MAPTSMN1; SMN2 | |
| SCHEMBL11496329 | 0.78 | SIGMAR1 (0.50) | CYP2C9MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL11493582 | 0.77 | DRD2 (0.47) | CYP2C9DRD2DRD3SMN1; SMN2L3MBTL1 | |
| SCHEMBL8734785 | 0.76 | ESR2 (0.48) | DRD2OPRM1DRD3MAPTALDH1A1 | |
| SCHEMBL11496278 | 0.76 | RECQL (0.44) | CYP2C9DRD2DRD3MAPTSMN1; SMN2 | |
| SCHEMBL11496471 | 0.74 | FDPS (0.45) | DRD2OPRM1DRD3HPGDGAA | |
| SCHEMBL11487487 | 0.74 | CHRM2 (0.43) | CYP2C9 | |
| SCHEMBL11492906 | 0.73 | DRD2 (0.47) | DRD2OPRM1DRD3HPGDGAA | |
| SCHEMBL11491847 | 0.72 | SMN1; SMN2 (0.39) | CYP2C9SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |