Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449608 | 0.81 | ALOX15 (0.68) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL588715 | 0.81 | ALDH1A1 (0.68) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL27660283 | 0.79 | ALOX15 (0.66) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| Hydrochloric Acid SCHEMBL28311112 | 0.79 | ALOX15 (0.66) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL23918517 | 0.78 | BCHE (0.69) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL29993 | 0.78 | ALDH1A1 (0.64) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL8736660 | 0.78 | ALOX15 (0.64) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| Ampyrone SCHEMBL11674586 | 0.78 | BCHE (1.00) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL151171 | 0.78 | ALOX15 (1.00) | ALOX15BCHEALDH1A1PTGS2LMNA | |
| SCHEMBL23907012 | 0.78 | BCHE (0.64) | ALOX15BCHEALDH1A1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8551445-B2 | Preparation and use of alkylating agents | THE QUEEN'S MEDICAL CENTER (US) | 2013-10-08 | — | — | US | claimed |
| US-20110028725-A1 | Preparation and Use of Alkylating Agents | THE QUEEN'S MEDICAL CENTER (US) | 2011-02-03 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-7776309-B2 | Preparation and use of alkylating agents | THE QUEEN'S MEDICAL CENTER (US) | 2010-08-17 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1660433-A2 | PREPARATION AND USE OF ALKYLATING AGENTS | The Queen's Medical Center (US) | 2006-05-31 | — | — | EP | claimed |
| US-20050123475-A1 | Preparation and use of alkylating agents | THE QUEEN'S MEDICAL CENTER | 2005-06-09 | — | — | US | claimed |
| WO-2005009928-A2 | PREPARATION AND USE OF ALKYLATING AGENTS | THE QUEEN'S MEDICAL CENTER (US) | 2005-02-03 | — | — | WO | claimed |
| EP-0165630-B1 | METHOD OF PREPARING A CHLORINATED, BROMINATED, RADIOBROMINATED, IODINATED AND/OR RADIOIODINATED, AROMATIC OR HETEROAROMATIC COMPOUND, AS WELL AS A KIT FOR PREPARING A DIAGNOSTIC COMPOSITION ON THE BASIS OF THIS COMPOUND | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0165630-A2 | Method of preparing a chlorinated, brominated, radiobrominated, iodinated and/or radioiodinated, aromatic or heteroaromatic compound, as well as a kit for preparing a diagnostic composition on the basis of this compound | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1985-12-27 | — | — | EP | claimed |
| WO-2026107422-A1 | 6-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-05-21 | — | — | WO | disclosed |
| WO-2025217094-A1 | INTERLEUKIN RECEPTOR-ASSOCIATED KINASE (IRAK) PROTAC DEGRADERS AND MEDICAL USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-10-16 | — | — | WO | disclosed |
| US-20250320190-A1 | Novel Inhibitors of Leucine Carboxyl Methyltransferase-1 (LCMT-1) and Methods of Use Thereof | UNIV TEMPLE (US) | 2025-10-16 | — | — | US | disclosed |
| US-4363793-A | Diagnostic radiopharmaceuticals for localization in target tissues exhibiting a regional pH shift relative to surrounding tissues | STATE UNIVERSITY OF NEW YORK (US) | 1982-12-14 | — | — | US | disclosed |
| US-4360511-A | Amines useful as brain imaging agents | MEDI-PHYSICS, INC. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4284619-A | INJECTING RADIOIODINE COMPOUND | MEDI-PHYSICS, INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050123475-A1 | Preparation and use of alkylating agents | MGMT, MCL1, TOP2A | ALOX15 4074/4885BCHE 1513/4885ALDH1A1 3209/4885 |
| US-20110028725-A1 | Preparation and Use of Alkylating Agents | MGMT, MCL1, TOP2A | ALOX15 4074/4885BCHE 1513/4885ALDH1A1 3209/4885 |
| US-20250320190-A1 | Novel Inhibitors of Leucine Carboxyl Methyltransferase-1 (LCMT-1) and Methods of Use Thereof | GNMT, BHMT, SHMT1 | ALOX15 1621/4885BCHE 372/4885ALDH1A1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.