Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496730 | 0.83 | ALDH1A1 (0.43) | ALDH1A1NPC1L3MBTL1GAAFFAR2 | |
| SCHEMBL11490044 | 0.77 | SIGMAR1 (0.42) | ALDH1A1NPC1GAASIGMAR1CNR2 | |
| SCHEMBL8987611 | 0.77 | NPC1 (0.42) | ALDH1A1NPC1L3MBTL1MAPTPSEN1 | |
| SCHEMBL8987641 | 0.74 | PYCR1 (0.51) | SIGMAR1KDM4EPOLB | |
| SCHEMBL11259082 | 0.74 | ALDH1A1 (0.63) | ALDH1A1NPC1L3MBTL1MAPTSIGMAR1 | |
| SCHEMBL14973631 | 0.74 | L3MBTL1 (0.53) | ALDH1A1NPC1L3MBTL1GAAMAPT | |
| SCHEMBL11494197 | 0.73 | CNR2 (0.48) | ALDH1A1NPC1GAACNR2MEN1 | |
| SCHEMBL11493894 | 0.73 | TMEM97 (0.44) | ALDH1A1GAAMAPTSIGMAR1CNR2 | |
| SCHEMBL4879817 | 0.72 | ALDH1A1 (0.41) | ALDH1A1NPC1L3MBTL1GAAMAPT | |
| SCHEMBL9201471 | 0.70 | TAAR1 (0.46) | ALDH1A1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |