SCHEMBL1149296

SCHEMBL1149296

Cc1ccc(CS(=O)(=O)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MEN1 O00255 2/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
IDO1 P14902 1/20 0.42
GAA P10253 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
POLB P06746 1/20 0.40
CNR2 P34972 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7243419 0.87 CA2 (0.40) KMT2AMEN1CA1CA2CA9
SCHEMBL11069054 0.81 CA2 (0.50) KMT2ACA2ALDH1A1TP53CYP2A6
SCHEMBL4400952 0.80 KMT2A (0.62) KMT2AMEN1CA1CA2CA9
SCHEMBL925715 0.78 KMT2A (0.50) KMT2AMEN1CA1CA2CA9
SCHEMBL29221410 0.78 CA2 (0.41) KMT2AMEN1CA1CA2CA9
SCHEMBL788780 0.78 KMT2A (0.50) KMT2AMEN1CA1CA2CA9
SCHEMBL515055 0.78 KMT2A (0.50) KMT2AMEN1CA1CA2CA9
SCHEMBL1500953 0.77 ENPP2 (0.46) CYP3A4CYP2C9
SCHEMBL4702032 0.77 KMT2A (0.49) KMT2AMEN1CA1CA2CA9
SCHEMBL6524000 0.76 KMT2A (0.48) KMT2AMEN1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112794818-A Preparation method of N-propylaminoquinolinone and application of N-propylaminoquinolinone in synthesis of abscisic acid agonist AM1 and derivatives thereof 邵阳学院 2021-05-14 CN claimed
CN-112778197-A Preparation method of novel abscisic acid agonist AM1 邵阳学院 2021-05-11 CN claimed
CN-104277000-A Abscisic acid receptor stimulant raw drug and preparation method thereof SHANGHAI LVANG BIOTECHNOLOGY CO LTD 2015-01-14 CN claimed
EP-0266891-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP claimed
US-4159979-A P-METHYLBENZYLSULFONYL GROUP FOR AMINO GROUPS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-07-03 US claimed
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
US-12583836-B2 Sulphonamide compounds Anaxis Pharma Pty Ltd (AU) 2026-03-24 US disclosed
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-03-10 US disclosed
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-03-03 US disclosed
EP-4168401-B1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-01-07 EP disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-0792873-A1 N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents American Cyanamid Company (US) 1997-09-03 EP disclosed
EP-0627443-B1 3,4'-DIDEOXYMYCAMINOSYLTYLONOLIDE DERIVATIVE AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU (JP) 1997-03-26 EP disclosed
US-5541303-A 3,4'-dideoxymycaminosltylonolide derivative and process for producing the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1996-07-30 US disclosed
EP-0627443-A1 3,4'-DIDEOXYMYCAMINOSYLTYLONOLIDE DERIVATIVE AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1994-12-07 EP disclosed
WO-1994018165-A1 SULFONAMIDE COMPOUNDS AS OPIOID K-RECEPTOR AGONISTS PFIZER INC. (US) 1994-08-18 WO disclosed
US-5093350-A DEHYDROCYCLOCLAUSENAMIDE, ITS PREPARATION AND USE IN TREATING CEREBRAL HYPOXIA BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
US-4237130-A DIURETICS, HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1980-12-02 US disclosed
US-4159979-A P-METHYLBENZYLSULFONYL GROUP FOR AMINO GROUPS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 KMT2A 3540/4885MEN1 3711/4885CA1 4697/4885
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer CKS2, CSNK2A3, CSNK1A1L KMT2A 1423/4885MEN1 3609/4885CA1 476/4885
US-12583836-B2 Sulphonamide compounds MLKL, RIPK3, CASP1 KMT2A 3281/4885MEN1 1760/4885CA1 1409/4885
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function CRBN, CD4, ICOS KMT2A 3331/4885MEN1 3857/4885CA1 414/4885
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 KMT2A 3540/4885MEN1 3711/4885CA1 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.