Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920622 | 0.74 | NT5E (0.30) | — | |
| SCHEMBL8627890 | 0.65 | — | — | |
| SCHEMBL21603060 | 0.65 | HSP90AA1 (0.31) | HSP90AA1HSP90AB1 | |
| SCHEMBL3704660 | 0.65 | CA2 (0.38) | HSP90AA1HSP90AB1KDM4ELMNA | |
| SCHEMBL27641092 | 0.64 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL18307332 | 0.64 | KDM4E (0.43) | HSP90AA1HSP90AB1KDM4ELMNA | |
| SCHEMBL17269959 | 0.62 | KDM4E (0.38) | HSP90AA1HSP90AB1KDM4ELMNA | |
| SCHEMBL1499299 | 0.62 | TRPV4 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL1149520 | 0.61 | — | — | |
| SCHEMBL25408294 | 0.61 | HSP90AA1 (0.31) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299262-B2 | Pyridylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-10-30 | — | — | US | disclosed |
| EP-2297134-A1 | SUBSTITUTED PYRIDIN-4 -YL-METHYL SULFONAMIDES AS FUNGICIDES | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20110065577-A1 | Substituted pyridin-4-yl-methyl sulfonamides as fungicides | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | BASF SE (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2262794-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2252600-A1 | SUBSTITUTED TRIAZINYLMETHYL SULFONAMIDES | BASF SE (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| EP-2231605-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009141274-A1 | SUBSTITUTED PYRIDIN-4 -YL-METHYL SULFONAMIDES AS FUNGICIDES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009112533-A1 | SUBSTITUTED TRIAZINYLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009103650-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009071448-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071449-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | STS, ARSA, CYP4X1 | HSP90AA1 2075/4885HSP90AB1 1949/4885KDM4E 705/4885 |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | STS, TST, TPST2 | HSP90AA1 1398/4885HSP90AB1 1057/4885KDM4E 1795/4885 |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | CBR3, CBR1, CBS | HSP90AA1 1979/4885HSP90AB1 1707/4885KDM4E 2704/4885 |
| US-20110065577-A1 | Substituted pyridin-4-yl-methyl sulfonamides as fungicides | CYP4X1, PNPO, PADI1 | HSP90AA1 3025/4885HSP90AB1 3210/4885KDM4E 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.