Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495603 | 1.00 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL25254429 | 0.83 | PPARG (0.60) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL25254297 | 0.79 | ALOX5 (0.64) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL11180363 | 0.77 | GAA (0.49) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL11180360 | 0.77 | GAA (0.49) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL14198023 | 0.74 | CYP1A1 (0.58) | ALDH1A1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL29105902 | 0.71 | NPC1 (0.55) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL20914971 | 0.71 | AKR1B10 (0.68) | ALDH1A1KDM4EGAAALOX5HPGD | |
| SCHEMBL30610033 | 0.71 | AKR1B10 (0.68) | ALDH1A1KDM4EGAAALOX5HPGD | |
| SCHEMBL7138832 | 0.71 | JUN (0.58) | KMT2AMEN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206225-A | ANALGESICS | PFIZER INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | disclosed |