Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.60 |
| ▸ | PTGES | O14684 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254297 | 0.93 | ALOX5 (0.64) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL11495602 | 0.83 | KMT2A (0.51) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL11495603 | 0.83 | KMT2A (0.51) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL25254374 | 0.79 | ALOX5 (0.62) | PPARGALOX5PTGESGAAALDH1A1 | |
| SCHEMBL25297359 | 0.79 | ALOX5 (0.58) | PPARGALOX5PTGESKDM4EALDH1A1 | |
| SCHEMBL25257077 | 0.78 | MAPT (0.61) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL25257221 | 0.77 | ALOX5 (0.65) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL25297025 | 0.77 | MEN1 (0.53) | PPARGALOX5PTGESGAAKDM4E | |
| SCHEMBL7138832 | 0.74 | JUN (0.58) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8558334 | 0.73 | RAB9A (0.69) | ALDH1A1POLBRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |