Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985210 | 0.82 | HSD17B1 (0.50) | HSD17B1HSD17B2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3609594 | 0.78 | MAPT (0.48) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL3943459 | 0.76 | BRAF (0.33) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL11508434 | 0.73 | BRAF (0.37) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL11245882 | 0.72 | CSNK2A1 (0.48) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL1858562 | 0.72 | EIF4E (0.61) | HSD17B1HSD17B2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8985182 | 0.70 | ALDH1A1 (0.42) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL11508548 | 0.69 | TSHR (0.51) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL11614949 | 0.68 | MEN1 (0.60) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19196215 | 0.68 | MAPT (0.58) | MAPTSMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150051-A | N-Cyanosulfonamide compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4080483-A | COATINGS, MOLDING MATERIALS, LAMINATION | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4075185-A | ADDITION POLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049711-A | POLYSULFONAMIDE MONOMERS | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3944526-A | N-cyanosulfonamide resins and intermediates therefor and products thereof | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |