Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MECP2 | P51608 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655555 | 0.76 | NPC1 (0.67) | TSHRNPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8985182 | 0.76 | ALDH1A1 (0.42) | TSHRSMN1; SMN2KDM4ECYP3A4MEN1 | |
| SCHEMBL3610229 | 0.72 | NOTUM (0.67) | TSHRNPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL14378791 | 0.70 | NPC1 (0.81) | TSHRNPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11508434 | 0.69 | BRAF (0.37) | NPC1SMN1; SMN2RAB9AKDM4EMEN1 | |
| SCHEMBL11507047 | 0.69 | HSD17B1 (0.49) | SMN1; SMN2KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL3943459 | 0.69 | BRAF (0.33) | SMN1; SMN2MEN1KMT2AMAPK1HPGD | |
| SCHEMBL12306757 | 0.69 | NPC1 (0.77) | TSHRNPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11635661 | 0.68 | NPC1 (0.56) | TSHRNPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL2295342 | 0.67 | KMT2A (0.53) | TSHRNPC1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150051-A | N-Cyanosulfonamide compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4080483-A | COATINGS, MOLDING MATERIALS, LAMINATION | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4075185-A | ADDITION POLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049711-A | POLYSULFONAMIDE MONOMERS | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3944526-A | N-cyanosulfonamide resins and intermediates therefor and products thereof | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |