Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500313 | 0.82 | ADRB1 (0.46) | MAPTALDH1A1L3MBTL1TP53ALOX12 | |
| Hydrochloric Acid SCHEMBL27601656 | 0.75 | ADRB1 (0.44) | MAPTHSD11B1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7079396 | 0.69 | MMP1 (0.39) | ALDH1A1TP53SMN1; SMN2LMNAKMT2A | |
| SCHEMBL2900748 | 0.69 | PLD1 (0.42) | MAPTALDH1A1L3MBTL1HTR7 | |
| SCHEMBL31232802 | 0.69 | PLD1 (0.42) | MAPTALDH1A1TP53SMN1; SMN2KMT2A | |
| SCHEMBL27758968 | 0.68 | ADRB1 (0.43) | MAPTALDH1A1SMN1; SMN2LMNAADRB1 | |
| SCHEMBL20271939 | 0.68 | LMNA (0.58) | MAPTALDH1A1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL21378121 | 0.68 | LMNA (0.58) | MAPTALDH1A1L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL1871493 | 0.68 | MAPT (0.63) | IKBKBCHUKMAPTHSD11B1ALDH1A1 | |
| SCHEMBL1964149 | 0.68 | PLD1 (0.40) | MAPTALDH1A1L3MBTL1KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159331-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |