Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.39 |
| ▸ | MMP9 | P14780 | 6/20 | 0.39 |
| ▸ | MMP13 | P45452 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | MMP12 | P39900 | 4/20 | 0.39 |
| ▸ | MMP14 | P50281 | 4/20 | 0.39 |
| ▸ | MMP16 | P51512 | 4/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.37 |
| ▸ | FEN1 | P39748 | 5/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | PRKCB | P05771 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | PRKACG | P22612 | 2/20 | 0.36 |
| ▸ | PRKACB | P22694 | 2/20 | 0.36 |
| ▸ | PRKCH | P24723 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072805 | 0.71 | ALDH1A1 (0.56) | MMP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11508844 | 0.69 | IKBKB (0.43) | MMP2SMN1; SMN2TP53KMT2AALDH1A1 | |
| SCHEMBL16796971 | 0.68 | RIPK1 (0.40) | — | |
| SCHEMBL5514181 | 0.67 | ALOX5AP (0.32) | MMP1MMP9MMP13ADAM17ALOX5AP | |
| SCHEMBL6190053 | 0.67 | SIGMAR1 (0.43) | PRKD1MEN1KMT2AHSD17B10HTT | |
| SCHEMBL8499875 | 0.67 | RIPK1 (0.40) | HSD17B10 | |
| SCHEMBL5321655 | 0.67 | RIPK1 (0.40) | HSD17B10 | |
| SCHEMBL19287702 | 0.65 | PRKACA (0.56) | ALOX5APFEN1PRKD3PRKCGPRKCB | |
| SCHEMBL31232802 | 0.64 | PLD1 (0.42) | SMN1; SMN2TP53TSHRKMT2ARAB9A | |
| SCHEMBL2900748 | 0.64 | PLD1 (0.42) | ALOX15TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022893-A1 | Hydroxamic and carboxylic acid derivatives | BAXTER ANDREW DOUGLAS (GB) | 2003-01-30 | — | — | US | disclosed |
| EP-1163213-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056704-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2000-09-28 | — | — | WO | disclosed |