Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127953 | 0.76 | ADRB1 (0.53) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL7230204 | 0.74 | ADRB1 (0.44) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL27544020 | 0.74 | ADRB1 (0.47) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL7258863 | 0.72 | ADRB1 (0.44) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL28408131 | 0.71 | ADRB1 (0.43) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL522461 | 0.71 | ADRB1 (0.43) | ADRB1SIRT6KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL11556533 | 0.71 | KCNJ1 (0.51) | KCNJ1KCNH2ALDH1A1MAPTPKM | |
| Hydrochloric Acid SCHEMBL27601656 | 0.69 | ADRB1 (0.44) | ADRB1SIRT6ALDH1A1LMNAMAPT | |
| SCHEMBL30165832 | 0.69 | ALDH1A1 (0.50) | ADRB1SIRT6ALDH1A1LMNAMAPT | |
| SCHEMBL11508844 | 0.68 | IKBKB (0.43) | ADRB1SIRT6ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356167-A | Chroman compounds as 5-HT1B antagon | ASTRAZENECA AB (SE) | 2009-01-28 | — | — | CN | disclosed |