Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | IL33 | O95760 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512485 | 0.96 | OPRK1 (0.57) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL23507317 | 0.88 | DRD2 (0.57) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL28907187 | 0.86 | ALDH1A1 (0.45) | OPRK1OPRM1MEN1KMT2APDCD1LG2 | |
| SCHEMBL18306590 | 0.85 | OPRK1 (0.49) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL22639701 | 0.85 | OPRK1 (0.49) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL11510687 | 0.85 | OPRK1 (0.47) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL18862021 | 0.83 | OPRK1 (0.52) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL11509424 | 0.83 | CHRNB2 (0.46) | OPRK1OPRM1MEN1KMT2APDCD1LG2 | |
| SCHEMBL11509549 | 0.82 | LTA4H (0.48) | OPRK1OPRM1PDCD1LG2CD274ALDH1A1 | |
| SCHEMBL8542014 | 0.81 | SMN1; SMN2 (0.50) | OPRK1OPRM1HRH3HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243440-A | Hexahydroxypyrrolo [3,4-c ] pyrrole derivatives useful as LOX inhibitors | 癌症研究协会皇家癌症医院 | 2021-01-19 | — | — | CN | disclosed |