Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11215924 | 0.83 | — | — | |
| SCHEMBL11514741 | 0.81 | — | — | |
| Potassium Ion SCHEMBL11515043 | 0.76 | TDP1 (0.32) | — | |
| Potassium Ion SCHEMBL11221285 | 0.74 | ACHE (0.33) | — | |
| Potassium Ion SCHEMBL11513116 | 0.72 | LMNA (0.42) | — | |
| Potassium Ion SCHEMBL11026203 | 0.71 | — | — | |
| Potassium Ion SCHEMBL11510513 | 0.71 | — | — | |
| Potassium Ion SCHEMBL11213613 | 0.70 | TP53 (0.32) | — | |
| SCHEMBL11511964 | 0.66 | TSHR (0.32) | — | |
| Potassium Ion SCHEMBL11210423 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161524-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-4134979-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |