Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736871 | 0.85 | LMNA (0.46) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL10204793 | 0.82 | GAA (0.53) | MTNR1AMTNR1BCYP1A2GAACYP2C9 | |
| SCHEMBL20592934 | 0.81 | LDHA (0.47) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL13059499 | 0.81 | ALDH1A1 (0.52) | PPARGPPARAALDH1A1TSHRLMNA | |
| SCHEMBL28371885 | 0.80 | CES2 (0.47) | RECQLALDH1A1CES2CES1 | |
| SCHEMBL10603038 | 0.79 | CHRM1 (0.51) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL11493984 | 0.78 | TDP1 (0.54) | MTNR1AMTNR1BALDH1A1TSHRMAPT | |
| SCHEMBL9715374 | 0.78 | PPARA (0.45) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL11756005 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL2464979 | 0.76 | CYP1A2 (0.48) | MTNR1AMTNR1BPPARGPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147791-A | 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4048318-A | 1-Substituted-1,2,4-triazole fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |