Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520696 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11519690 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11520152 | 0.73 | KDM4E (0.35) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11521062 | 0.70 | FASN (0.36) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11520324 | 0.69 | KDM4E (0.38) | TRPM8ALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL11468500 | 0.68 | TRPM8 (0.40) | TRPM8ALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL11517772 | 0.66 | KMT2A (0.34) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11508179 | 0.66 | LMNA (0.33) | TRPM8ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11517299 | 0.66 | KMT2A (0.34) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL11516820 | 0.65 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |