Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521062 | 0.80 | FASN (0.36) | KDM4ECHRM2CHRM3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11520696 | 0.79 | ALDH1A1 (0.38) | KDM4ECHRM2CHRM3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11519690 | 0.78 | SMN1; SMN2 (0.44) | KDM4ECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11446778 | 0.77 | OPRM1 (0.38) | KDM4ECHRM2CHRM3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11334445 | 0.74 | KDM4E (0.40) | KDM4ECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11517756 | 0.73 | TRPM8 (0.40) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11517772 | 0.69 | KMT2A (0.34) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11517299 | 0.69 | KMT2A (0.34) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11507801 | 0.68 | CHRM2 (0.38) | KDM4ECHRM2CHRM3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11472504 | 0.67 | MEN1 (0.37) | KDM4ECHRM2CHRM3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |