Sugi Predict

Sugi Predict / Compounds / SCHEMBL11518261

SCHEMBL11518261

SCHEMBL11518261

N#Cc1ccc2ocnc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 1/20 0.47
▸ DYRK1A Q13627 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.44
▸ GAA P10253 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ CTNNB1 P35222 3/20 0.40
▸ WNT3A P56704 3/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NOS3 P29474 1/20 0.39
▸ NOS1 P29475 1/20 0.39
▸ NOS2 P35228 1/20 0.39
▸ NOTUM Q6P988 2/20 0.38
▸ LRRK2 Q5S007 1/20 0.36
▸ XDH P47989 1/20 0.35
▸ SLC22A12 Q96S37 1/20 0.35
▸ MAP4K4 O95819 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2229468 0.98 CYP2A6 (0.46) CYP2A6DYRK1AALDH1A1GAAMEN1
SCHEMBL28042705 0.85 DYRK1A (0.45) CYP2A6DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL26790771 0.81 DYRK1A (0.45) DYRK1AALDH1A1GAAMEN1KMT2A
SCHEMBL7217503 0.81 MEN1 (0.47) DYRK1AALDH1A1GAAMEN1KMT2A
SCHEMBL26790777 0.77 MEN1 (0.44) DYRK1AALDH1A1GAAMEN1KMT2A
SCHEMBL31701008 0.74 HSPD1 (0.61) —
SCHEMBL29040303 0.73 DYRK1A (0.39) DYRK1AALDH1A1GAAMEN1KMT2A
SCHEMBL28048555 0.73 DYRK1A (0.72) DYRK1AALDH1A1GAAMEN1KMT2A
SCHEMBL22995342 0.72 CHRNB2 (0.39) DYRK1AALDH1A1GAAMEN1KMT2A
Water SCHEMBL3527021 0.72 ALDH1A1 (0.50) DYRK1AALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 — — US claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 — — US claimed
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-12 — — US disclosed
US-20250171437-A1 (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA AGIOS PHARMACEUTICALS, INC. 2025-05-29 — — US disclosed
WO-2024257966-A1 HIGH-REFRACTIVE-INDEX ORGANIC MATERIAL AND LIGHT-EMITTING DEVICE COMPRISING SAME 비피시 주식회사 2024-12-19 — — WO disclosed
CN-114269725-B Anti-influenza virus compound, preparation method and application thereof 西藏海思科制药有限公司 2024-09-17 — — CN disclosed
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-02-16 — — US disclosed
CN-114269725-A Anti-influenza virus compound and preparation method and application thereof 四川海思科制药有限公司 2022-04-01 — — CN disclosed
EP-3036305-B1 COMPOUNDS WITH TERMINAL HETEROARYLCYANOVINYLENE GROUPS AND THEIR USE IN ORGANIC SOLAR CELLS BASF SE (DE) 2019-04-17 — — EP disclosed
US-9917260-B2 Compounds with terminal heteroarylcyanovinylene groups and their use in organic solar cells BASF SE (DE) 2018-03-13 — — US disclosed
US-9917260-B2 Compounds with terminal heteroarylcyanovinylene groups and their use in organic solar cells BASF SE (DE) 2018-03-13 — — US disclosed
US-9056874-B2 Complement pathway modulators and uses thereof NOVARTIS AG (CH) 2015-06-16 — — US disclosed
WO-2015024848-A1 COMPOUNDS WITH TERMINAL HETEROARYLCYANOVINYLENE GROUPS AND THEIR USE IN ORGANIC SOLAR CELLS BASF SE (DE) 2015-02-26 — — WO disclosed
US-20130296377-A1 Complement pathway modulators and uses thereof NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2013-11-07 — — US disclosed
CN-101410385-B Benzothiazoles having histamine H3 receptor activity HIGH POINT PHARMACEUTICALS LLC 2011-08-24 — — CN disclosed
CN-101410385-A Benzothiazoles having histamine H3 receptor activity HIGH POINT PHARMACEUTICALS LLC (US) 2009-04-15 — — CN disclosed
CN-1520298-A Pyrazolopyrimidines as therapeutic agents �����ʩ���عɷݹ�˾ 2004-08-11 — — CN disclosed
US-4179296-A CONTAINING A BENZIMIDAZOLOCARBOCYANINE DYE AND AT LEAST ONE OTHER CYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-12-18 — — US disclosed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 — — US disclosed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES DDT, CRY1, CYP4F3 CYP2A6 239/4885DYRK1A 510/4885ALDH1A1 3433/4885
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides DDT, CRY1, AAAS CYP2A6 225/4885DYRK1A 371/4885ALDH1A1 3552/4885
US-20250171437-A1 (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA PAH, BCKDK, PKM CYP2A6 427/4885DYRK1A 1030/4885ALDH1A1 634/4885
US-20130296377-A1 Complement pathway modulators and uses thereof C5, C3AR1, C9 CYP2A6 493/4885DYRK1A 4409/4885ALDH1A1 2495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.