Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.56 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.56 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.56 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564156 | 0.90 | PTGS2 (0.61) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL374641 | 0.86 | FTO (0.71) | PTGS2TTRPTGS1MT-CO2ADRA1A | |
| SCHEMBL374772 | 0.83 | PTGS2 (0.55) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL11517374 | 0.83 | CLCN2 (0.53) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL11564152 | 0.83 | MT-CO2 (0.78) | PTGS2TTRPTGS1MT-CO2ADRA1A | |
| SCHEMBL11407549 | 0.81 | CXCL8 (0.55) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL9735209 | 0.80 | FTO (0.56) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL11451926 | 0.79 | PTGS2 (0.72) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| SCHEMBL11516532 | 0.78 | METTL3 (0.58) | PTGS2TTRPTGS1CXCL8MT-CO2 | |
| Acetamide SCHEMBL27431923 | 0.78 | CXCL8 (0.57) | PTGS2TTRPTGS1CXCL8MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166128-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENTS, RHEUMATIC DISEASES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4166128-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENTS, RHEUMATIC DISEASES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-08-28 | — | — | US | disclosed |