Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359088 | 0.72 | PDE4B (0.39) | FGFR1FGFR2FGFR4FGFR3KDM4E | |
| SCHEMBL10964297 | 0.71 | LMNA (0.36) | KDM4ELMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10688416 | 0.71 | MAPT (0.36) | KDM4ELMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL214204 | 0.71 | L3MBTL1 (0.36) | KDM4ELMNAALDH1A1TSHRNPC1 | |
| SCHEMBL7761880 | 0.69 | TSHR (0.39) | FGFR1FGFR2FGFR4FGFR3KDM4E | |
| SCHEMBL692285 | 0.68 | FGFR1 (0.43) | FGFR1FGFR2FGFR4FGFR3KDM4E | |
| SCHEMBL10754881 | 0.67 | FGFR1 (0.39) | FGFR1FGFR2FGFR4FGFR3KDM4E | |
| SCHEMBL28035650 | 0.67 | KIF11 (0.38) | KDM4ELMNAALDH1A1TSHRTP53 | |
| SCHEMBL8656807 | 0.66 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3LMNA | |
| SCHEMBL29273155 | 0.66 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144067-A | DIAZO RESIN, FISH GLUE BINDER | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |