Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964297 | 0.74 | LMNA (0.36) | BACE1HPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10359088 | 0.71 | PDE4B (0.39) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL10688416 | 0.69 | MAPT (0.36) | HPGDALDH1A1KDM4ELMNAHTT | |
| SCHEMBL214204 | 0.69 | L3MBTL1 (0.36) | ALDH1A1KDM4ETSHRLMNAHTT | |
| SCHEMBL11519983 | 0.67 | FGFR1 (0.43) | ALDH1A1KDM4ETSHRLMNATP53 | |
| SCHEMBL7761880 | 0.64 | TSHR (0.39) | BACE1ALDH1A1KDM4ETSHRHDAC6 | |
| SCHEMBL8970861 | 0.64 | ALDH1A1 (0.44) | ALDH1A1KDM4ECYP1A2CYP2C9PKM | |
| SCHEMBL28384827 | 0.63 | BACE1 (0.42) | KIF11BACE1HPGDALDH1A1KDM4E | |
| Biphenyl SCHEMBL27543247 | 0.58 | ALDH1A1 (0.64) | KIF11BACE1ALDH1A1CYP1A2TSHR | |
| SCHEMBL1326009 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910167-B | 1H-furo [2,3-c] pyrazole derivative, synthetic method therefor and applications | 浙江师范大学 | 2017-05-03 | — | — | CN | claimed |
| CN-104910167-B | 1H-furo [2,3-c] pyrazole derivative, synthetic method therefor and applications | 浙江师范大学 | 2017-05-03 | — | — | CN | disclosed |
| CN-104910167-A | 1H-furo [2,3-c] pyrazole derivative, synthetic method therefor and applications | UNIV ZHEJIANG NORMAL | 2015-09-16 | — | — | CN | disclosed |