SCHEMBL11522162

SCHEMBL11522162

FC(Br)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455527 0.79 TDP1 (0.40) TDP1APEX1
SCHEMBL328794 0.79 TDP1 (0.40) TDP1APEX1
SCHEMBL4601560 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL5186322 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL9373547 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL2882117 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL4453850 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL4599386 0.73 TDP1 (0.41) TDP1APEX1
SCHEMBL31349336 0.72 GABRA1 (0.41) TDP1APEX1
SCHEMBL10455644 0.72 GABRA1 (0.41) TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed