SCHEMBL4453850

SCHEMBL4453850

ClC(Br)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328794 0.79 TDP1 (0.40) TDP1APEX1
SCHEMBL4455527 0.79 TDP1 (0.40) TDP1APEX1
SCHEMBL11522162 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL2882117 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL4601560 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL5186322 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL11398915 0.75
SCHEMBL9373547 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL4599386 0.73 TDP1 (0.41) TDP1APEX1
SCHEMBL10455644 0.72 GABRA1 (0.41) TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113174000-B Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2022-07-26 CN claimed
CN-113174000-A Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2021-07-27 CN claimed
CN-113174000-B Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2022-07-26 CN disclosed
CN-113174000-A Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2021-07-27 CN disclosed
US-9573878-B2 Process for the preparation of the monomer pentabromobenzyl acrylate and polymerization thereof BROMINE COMPOUNDS LTD. (IL) 2017-02-21 US disclosed
US-20160107979-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF BROMINE COMPOUNDS LTD. (IL) 2016-04-21 US disclosed
US-9255165-B2 Poly (pentabromobenzyl acrylate) and its properties BROMINE COMPOUNDS LTD. (IL) 2016-02-09 US disclosed
US-20150191559-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF BROMINE COMPOUNDS LTD (IL) 2015-07-09 US disclosed
US-9018324-B2 Process for the preparation of the monomer pentabromobenzyl acrylate and polymerization thereof BROMINE COMPOUNDS LTD. (IL) 2015-04-28 US disclosed
EP-2697272-B1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF BROMINE COMPOUNDS LTD (IL) 2015-02-18 EP disclosed
US-20140121338-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF BROMINE COMPOUNDS LTD. (IL) 2014-05-01 US disclosed
WO-2006008738-A1 SYNTHESIS OF AROMATIC POLYHALOGENATED HALOMETHYL COMPOUNDS BROMINE COMPOUNDS LTD. (IL) 2006-01-26 WO disclosed
US-6028156-A Process for the preparation of poly-(halobenzyl acrylate) BROMINE COMPOUNDS, LTD. (IL) 2000-02-22 US disclosed
US-4283565-A REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY DYNAMIT NOBEL AG (DE) 1981-08-11 US disclosed
US-4212996-A USING AN IRON OR ALUMINUM MASKING (COMPLEXING) AGENT CONTAINING AMINOACETIC ACID GROUPS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4211730-A HALOBROMOBENZYL ACRYLATE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-4128709-A Acrylate-based polymers and their use as flameproofing agents DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4119612-A Polymeric and oligomeric formals DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4059618-A CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-4059618-A CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160107979-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF ACR, MMAB, ALKBH3 TDP1 2155/4885APEX1 1048/4885
US-20140121338-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF ACR, ALKBH3, ALK TDP1 2206/4885APEX1 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.