Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526152 | 0.88 | RAB9A (0.42) | MAPTNPSR1TYK2NPC1KDM4E | |
| SCHEMBL11373408 | 0.86 | TDP1 (0.51) | HCRTR1P2RX7SMN1; SMN2NPC1KDM4E | |
| SCHEMBL11519411 | 0.83 | RAB9A (0.47) | MAPTTYK2NPC1KDM4ERAB9A | |
| SCHEMBL8657584 | 0.82 | RAB9A (0.57) | HCRTR1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11521954 | 0.82 | TYK2 (0.44) | P2RX7MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11379058 | 0.81 | TYK2 (0.45) | P2RX7MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11522976 | 0.81 | RAB9A (0.45) | MAPTTYK2NPC1KDM4ERAB9A | |
| SCHEMBL11524573 | 0.81 | RAB9A (0.46) | MEN1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11524635 | 0.80 | TYK2 (0.43) | MEN1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11524433 | 0.80 | MEN1 (0.45) | MEN1MAPTKMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | claimed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |