Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522493 | 0.80 | RAB9A (0.44) | RORCNPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11521954 | 0.79 | TYK2 (0.44) | TYK2RORCNPC1KDM4EALDH1A1 | |
| SCHEMBL11523665 | 0.78 | HCRTR1 (0.48) | TYK2RORCNPC1KDM4EALDH1A1 | |
| SCHEMBL11522756 | 0.78 | KDM4E (0.48) | TYK2RORCNPC1KDM4EALDH1A1 | |
| SCHEMBL11524635 | 0.76 | TYK2 (0.43) | TYK2RORCNPC1KDM4EALDH1A1 | |
| SCHEMBL8657584 | 0.76 | RAB9A (0.57) | NPC1RAB9ARPS6KA3MEN1MAPT | |
| SCHEMBL11519411 | 0.74 | RAB9A (0.47) | TYK2NPC1KDM4ERAB9AMAPT | |
| SCHEMBL11526152 | 0.74 | RAB9A (0.42) | TYK2NPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL11524573 | 0.72 | RAB9A (0.46) | TYK2NPC1RAB9AMEN1MAPT | |
| SCHEMBL11522976 | 0.72 | RAB9A (0.45) | TYK2NPC1KDM4ERAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |