Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519758 | 0.81 | LMNA (0.38) | ALDH1A1LMNAIDO1KDM4ENPC1 | |
| SCHEMBL8755288 | 0.78 | ACHE (0.40) | ACHETDP1ALDH1A1LMNANPSR1 | |
| SCHEMBL10444591 | 0.78 | ESR1 (0.38) | ALDH1A1LMNATP53MAPT | |
| SCHEMBL11527676 | 0.76 | CA1 (0.46) | ACHETDP1ALDH1A1LMNANPSR1 | |
| SCHEMBL11518026 | 0.76 | ALDH1A1 (0.46) | TDP1ALDH1A1NPC1TP53RAB9A | |
| SCHEMBL10533114 | 0.76 | CYP1A2 (0.39) | TDP1ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL10320159 | 0.74 | AR (0.40) | ACHETDP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL5034146 | 0.74 | ACHE (0.47) | ACHETDP1ALDH1A1LMNAKDM4E | |
| SCHEMBL1798922 | 0.74 | ACHE (0.47) | ACHETDP1ALDH1A1LMNAKDM4E | |
| SCHEMBL80628 | 0.74 | ACHE (0.47) | ACHETDP1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175091-A | Substituted 3,1-benzazasilines | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |