Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335268 | 0.66 | ADRB2 (0.43) | ADRB2ADRB1CYP2D6ADRB3ALDH1A1 | |
| SCHEMBL14461591 | 0.64 | LMNA (0.41) | KMT2APKMADRB2ADRB1CYP2D6 | |
| SCHEMBL11580223 | 0.63 | MCHR1 (0.49) | KMT2APKMTDP1HPGD | |
| SCHEMBL12971937 | 0.63 | CYP19A1 (0.36) | KMT2AALDH1A1MAPTNPC1EPHX2 | |
| SCHEMBL6641423 | 0.62 | TDP1 (0.42) | KMT2AADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL18911195 | 0.62 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPTEPHX2HPGD | |
| SCHEMBL7897828 | 0.62 | SIGMAR1 (0.67) | ADRB2ADRB1CYP2D6ADRB3ALDH1A1 | |
| SCHEMBL7868616 | 0.61 | ADRB2 (0.58) | ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL18905382 | 0.61 | CYP19A1 (0.37) | KMT2APKMALDH1A1MAPTEPHX2 | |
| SCHEMBL4374759 | 0.60 | SLC6A4 (0.42) | KMT2APKMSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157400-A | BLOCKING, AGENTS, HYPOTENSIVES, TRANQUILIZERS | MAR-PHA, SOCIETE D'ETUDE ET D'EXPLOITATION DE MARQUES (FR) | 1979-06-05 | — | — | US | disclosed |