SCHEMBL11524166

SCHEMBL11524166

CCCCC(Cl)OOC(=O)Cl

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.37
CA1 P00915 4/20 0.37
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.36
TSHR P16473 3/20 0.34
FDPS P14324 1/20 0.33
CYP3A4 P08684 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10878549 0.79 CA2 (0.39) CA2CA1ALDH1A1TP53MAPK1
SCHEMBL28449715 0.78 DNM1 (0.39) CA2CA1ALDH1A1MAPK1TSHR
SCHEMBL31112487 0.73 FAAH (0.41) CA2CA1ALDH1A1TP53TSHR
SCHEMBL7207177 0.72 CA2 (0.41) CA2CA1ALDH1A1TP53MAPK1
SCHEMBL31112442 0.72 GPR84 (0.44) CA2ALDH1A1TSHRZDHHC7GPR84
SCHEMBL31112441 0.72 GPR84 (0.44) CA2ALDH1A1TSHRZDHHC7GPR84
SCHEMBL7686574 0.71 ALDH1A1 (0.41) CA2CA1ALDH1A1MAPK1TSHR
SCHEMBL7207181 0.71 CA2 (0.43) CA2CA1MAPK1FDPSSLC1A3
SCHEMBL27324758 0.69 NAAA (0.41) CA2CA1ALDH1A1MAPK1TSHR
SCHEMBL27576843 0.69 FAAH (0.45) CA2CA1MAPK1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132731-A X-RAY CONTRAST AGENT SCHERING AKTIENGESELLSCHAFT (DE) 1979-01-02 US disclosed