Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937859 | 0.85 | AOC3 (0.36) | LMNAHSD17B10TLR8MEN1KMT2A | |
| SCHEMBL2876075 | 0.73 | ALOX15 (0.41) | HTTLMNALTA4HALDH1A1POLB | |
| SCHEMBL13727051 | 0.72 | LMNA (0.30) | LMNA | |
| SCHEMBL7606690 | 0.71 | NOS3 (0.31) | — | |
| SCHEMBL12820952 | 0.70 | PKM (0.46) | TLR8MCHR1KDM4EPKM | |
| SCHEMBL10998377 | 0.69 | DHFR (0.33) | — | |
| SCHEMBL15196099 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL11790398 | 0.68 | AOC3 (0.37) | LMNAHSD17B10TLR8MEN1KMT2A | |
| SCHEMBL5500327 | 0.67 | PDE10A (0.36) | KMT2AMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL13829729 | 0.67 | CNR1 (0.44) | HTTLMNATLR8MCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162310-A | Combating arthropods with O-alkyl-O-[5-substituted-pyrimidin(4)-yl]-(thiono)(thiol)-phosphoric(phosphonic)acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |