Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417837 | 0.87 | LMNA (0.55) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL9417792 | 0.86 | RXRA (0.54) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL30096449 | 0.81 | KDM4E (0.51) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL11524880 | 0.81 | KLKB1 (0.50) | MAPTHSD17B10KDM4EALOX15HPGD | |
| SCHEMBL9417833 | 0.78 | ALDH1A1 (0.64) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL17121759 | 0.77 | KMT2A (0.63) | SHBGHSP90AA1MAPTHSD17B10KDM4E | |
| SCHEMBL18241740 | 0.77 | MAPT (0.49) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL12553675 | 0.76 | MAPT (0.53) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL31335625 | 0.76 | MAPT (0.53) | SHBGHSP90AA1HSP90AB1MAPTHSD17B10 | |
| SCHEMBL9417779 | 0.75 | MRGPRX4 (0.46) | MAPTHSD17B10KDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |