SCHEMBL11525599

SCHEMBL11525599

O=C(Cl)c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.56
RARB P10826 2/20 0.56
RARG P13631 2/20 0.56
KDM4E B2RXH2 5/20 0.52
ALDH1A1 P00352 3/20 0.52
PTGS2 P35354 2/20 0.52
PTGDR2 Q9Y5Y4 5/20 0.50
CDC7 O00311 2/20 0.50
DBF4 Q9UBU7 2/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
POLB P06746 1/20 0.49
CCNE1 P24864 1/20 0.48
CDK2 P24941 1/20 0.48
ALOX5 P09917 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527790 0.86 PTGDR2 (0.47) RARARARBRARGKDM4EALDH1A1
SCHEMBL9768642 0.82 ALDH1A1 (0.62) KDM4EALDH1A1PTGS2PTGDR2CDC7
SCHEMBL11460695 0.80 KDM4E (0.58) KDM4EALDH1A1PTGS2PTGDR2CYP1A2
SCHEMBL11284205 0.80 KDM4E (0.58) KDM4EALDH1A1PTGS2PTGDR2CYP1A2
SCHEMBL3056066 0.80 CDC7 (0.65) RARARARBRARGKDM4EALDH1A1
SCHEMBL11462189 0.80 KDM4E (0.58) KDM4EALDH1A1PTGS2PTGDR2CYP1A2
SCHEMBL11524489 0.78 CSNK2A2 (0.51) RARARARBRARGKDM4EALDH1A1
SCHEMBL21670773 0.78 PTGS2 (0.56) KDM4EALDH1A1PTGS2PTGDR2CDC7
SCHEMBL12245630 0.76 ALOX5 (0.69) RARARARBRARGKDM4EALDH1A1
SCHEMBL11287147 0.76 PTGS2 (0.74) KDM4EALDH1A1PTGS2PTGDR2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed