Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | RXRB | P28702 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531739 | 0.89 | KDM4E (0.45) | RXRARXRBSRD5A2SRD5A1ALDH1A1 | |
| SCHEMBL11532625 | 0.87 | SRD5A2 (0.55) | RXRARXRBSRD5A2SRD5A1ALDH1A1 | |
| SCHEMBL11532467 | 0.86 | RHEB (0.55) | RXRARXRBALDH1A1RHEBNPC1 | |
| SCHEMBL11604724 | 0.79 | XDH (0.42) | ALDH1A1CA9KMT2AHPGD | |
| SCHEMBL11607350 | 0.78 | CNR2 (0.47) | ALDH1A1CA9HPGD | |
| SCHEMBL11591989 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AHPGD | |
| SCHEMBL18989127 | 0.75 | LMNA (0.47) | RXRARXRBSRD5A2SRD5A1ALDH1A1 | |
| SCHEMBL11606291 | 0.75 | XDH (0.46) | ALDH1A1 | |
| SCHEMBL11607595 | 0.73 | PTGER1 (0.46) | ALDH1A1RHEBKMT2AMRGPRX4SMN1; SMN2 | |
| SCHEMBL14332793 | 0.73 | KDM4E (0.53) | ALDH1A1LMNARAB9ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156728-A | HYPOTENSIVE | MEIJI SEIKA KAISHA, LTD. (JP) | 1979-05-29 | — | — | US | disclosed |
| US-4083850-A | HYPOTENSIVE AGENTS | MEIJI SEIKA KAISHA LTD. (JA) | 1978-04-11 | — | — | US | disclosed |