Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604724 | 0.79 | XDH (0.42) | XDHALDH1A1 | |
| SCHEMBL11605400 | 0.79 | XDH (0.43) | XDHALDH1A1GAA | |
| SCHEMBL11607350 | 0.78 | CNR2 (0.47) | XDHALDH1A1 | |
| SCHEMBL11591989 | 0.77 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL14332793 | 0.76 | KDM4E (0.53) | ALDH1A1GAA | |
| SCHEMBL11605305 | 0.76 | ALOX15 (0.42) | ALDH1A1GAAHIF1A | |
| SCHEMBL11603141 | 0.76 | AKR1C3 (0.37) | ALDH1A1GAA | |
| SCHEMBL11605247 | 0.75 | TSHR (0.49) | ALDH1A1GAA | |
| SCHEMBL11532625 | 0.75 | SRD5A2 (0.55) | ALDH1A1 | |
| SCHEMBL11538794 | 0.75 | RXRA (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083850-A | HYPOTENSIVE AGENTS | MEIJI SEIKA KAISHA LTD. (JA) | 1978-04-11 | — | — | US | disclosed |