Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461238 | 0.82 | CA2 (0.35) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL553792 | 0.71 | NPC1 (0.35) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL1375450 | 0.71 | NPC1 (0.35) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL3267875 | 0.70 | MAPT (0.35) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL10841005 | 0.69 | NPC1 (0.39) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL1629578 | 0.69 | NPC1 (0.39) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL374979 | 0.69 | ALDH1A1 (0.33) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL3266678 | 0.68 | MEN1 (0.41) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL15010759 | 0.67 | POLB (0.33) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL4838387 | 0.67 | HTR2A (0.36) | NPC1RAB9AMITFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292347-A1 | DIHETEROCYCLIC TRIAZINONE NUCLEOSIDE ANALOGS AND THEIR USE FOR MEDICATION | XU LIFENG (US) | 2021-09-23 | — | — | US | claimed |
| EP-1599555-B1 | CMP COMPOSITION COMPRISING A SULFONIC ACID AND A METHOD FOR POLISHING NOBLE METALS | CABOT MICROELECTRONICS CORP (US) | 2019-06-12 | — | — | EP | claimed |
| EP-3125857-A1 | COMPOSITIONS AND METHODS FOR ENHANCING THE TOPICAL APPLICATION OF A BASIC BENEFIT AGENT | Johnson & Johnson Consumer Inc. (US) | 2017-02-08 | — | — | EP | claimed |
| US-9474699-B2 | Compostions and methods for enhancing the topical application of a basic benefit agent | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-10-25 | — | — | US | claimed |
| WO-2015153074-A1 | COMPOSITIONS AND METHODS FOR ENHANCING THE TOPICAL APPLICATION OF A BASIC BENEFIT AGENT | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-10-08 | — | — | WO | claimed |
| US-20150272834-A1 | COMPOSTIONS AND METHODS FOR ENHANCING THE TOPICAL APPLICATION OF A BASIC BENEFIT AGENT | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2015-10-01 | — | — | US | claimed |
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | LIAONING LIFENG SCIENT & TECHNOLOGY DEV COMPANY LTD (CN) | 2015-06-04 | — | — | US | claimed |
| JP-4709136-B2 | — | — | 2011-06-22 | — | — | JP | claimed |
| WO-2007145991-A2 | ANTI-INFLAMMATORY AND ANALGESIC COMPOSITIONS AND RELATED METHODS | LIPOCINE, INC. (US) | 2007-12-21 | — | — | WO | claimed |
| US-20070281927-A1 | Anti-inflammatory and analgesic compositions and related methods | LIPOCINE, INC. | 2007-12-06 | — | — | US | claimed |
| US-20050181041-A1 | Method of preparation of mixed phase co-crystals with active agents | MEDCRYSTALFORMS, LLC (US) | 2005-08-18 | — | — | US | claimed |
| WO-2005055983-A2 | METHOD OF PREPARATION OF MIXED PHASE CO-CRYSTALS WITH ACTIVE AGENTS | MEDCRYSTALFORMS, LLC (US) | 2005-06-23 | — | — | WO | claimed |
| WO-2004076574-A2 | CMP COMPOSITION COMPRISING A SULFONIC ACID AND A METHOD FOR POLISHING NOBLE METALS | CABOT MICROELECTRONICS CORPORATION (US) | 2004-09-10 | — | — | WO | claimed |
| US-20030181142-A1 | CMP method for noble metals | CABOT MICROELECTRONICS CORPORATION | 2003-09-25 | — | — | US | claimed |
| EP-1210063-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | Lipocine, Inc. (US) | 2002-06-05 | — | — | EP | claimed |
| US-6383471-B1 | DRUG DELIVERY | LIPOCINE, INC. | 2002-05-07 | — | — | US | claimed |
| EP-1165048-A1 | COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS | Lipocine, Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| US-6309663-B1 | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents | LIPOCINE INC. | 2001-10-30 | — | — | US | claimed |
| WO-2001012155-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | LIPOCINE, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| WO-2000059475-A1 | COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS | LIPOCINE, INC. (US) | 2000-10-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292347-A1 | DIHETEROCYCLIC TRIAZINONE NUCLEOSIDE ANALOGS AND THEIR USE FOR MEDICATION | NTPCR, ENTPD5, DPYD | NPC1 132/4885RAB9A 2561/4885MITF 1549/4885 |
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | CYP11B1, CYP51A1, CYP11B2 | NPC1 115/4885RAB9A 427/4885MITF 1344/4885 |
| US-20070281927-A1 | Anti-inflammatory and analgesic compositions and related methods | MB, PTGS1, PTGS2 | NPC1 3650/4885RAB9A 4273/4885MITF 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.