Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670688 | 0.86 | HSD17B1 (0.51) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13319554 | 0.85 | HSD17B1 (0.53) | HSD17B1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL11705750 | 0.84 | HSD17B1 (0.68) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5549813 | 0.83 | MMP1 (0.49) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11542474 | 0.81 | NR4A1 (0.45) | HSD17B1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL11542478 | 0.81 | NR4A1 (0.45) | HSD17B1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL11544146 | 0.79 | SLC6A3 (0.38) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11544143 | 0.79 | SLC6A3 (0.38) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4641337 | 0.79 | MAPT (0.55) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL177294 | 0.78 | MAPT (0.64) | HSD17B1MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |