Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544143 | 1.00 | SLC6A3 (0.38) | SLC6A3LTB4RSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL11542478 | 0.86 | NR4A1 (0.45) | LTB4RMMP2MMP9MMP8MMP13 | |
| SCHEMBL11542474 | 0.86 | NR4A1 (0.45) | LTB4RMMP2MMP9MMP8MMP13 | |
| SCHEMBL11543256 | 0.85 | F2 (0.38) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL11543258 | 0.85 | F2 (0.38) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL22390293 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL22390294 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL11543441 | 0.79 | HSD17B1 (0.51) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL11485877 | 0.77 | MTNR1A (0.40) | SMN1; SMN2HDAC1MAPTALDH1A1RAB9A | |
| SCHEMBL11485879 | 0.77 | MTNR1A (0.40) | SMN1; SMN2HDAC1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |