Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24496705 | 0.80 | HDAC4 (0.45) | RAB9AHTTNPC1HPGDPOLB | |
| SCHEMBL29586755 | 0.80 | HDAC4 (0.45) | RAB9AHTTNPC1HPGDPOLB | |
| SCHEMBL4651767 | 0.79 | RAB9A (0.71) | KMT2ARAB9ALMNAHTTMEN1 | |
| SCHEMBL1689630 | 0.77 | KMT2A (0.55) | KMT2AMEN1HPGDALDH1A1SIRT1 | |
| SCHEMBL11496018 | 0.76 | HDAC3 (0.56) | KMT2ARAB9ALMNAHTTMEN1 | |
| SCHEMBL2685855 | 0.75 | SIRT1 (0.58) | SIRT1 | |
| SCHEMBL925260 | 0.75 | SIRT1 (0.48) | KMT2ARAB9AHTTNPC1HPGD | |
| SCHEMBL31566197 | 0.75 | SIRT1 (0.58) | SIRT1 | |
| SCHEMBL11530821 | 0.74 | LMNA (0.47) | KMT2ARAB9ALMNAHTTMEN1 | |
| SCHEMBL2616331 | 0.74 | ALDH1A1 (0.44) | RAB9AHTTNPC1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164576-A | LIPOGENESIS INHIBITORS IN MAMMALS | SHELL OIL COMPANY (US) | 1979-08-14 | — | — | US | disclosed |