Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544979 | 0.78 | LMNA (0.34) | NPSR1ALDH1A1SYKGAAMAPT | |
| SCHEMBL11544998 | 0.78 | ALOX5 (0.36) | NPSR1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL11544871 | 0.76 | PARP1 (0.39) | ALDH1A1PARP1SYKGAAMAPT | |
| SCHEMBL11543960 | 0.74 | MAPT (0.38) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11545923 | 0.72 | KMT2A (0.43) | NPSR1ALDH1A1PARP1GAAMAPT | |
| SCHEMBL11545794 | 0.71 | NEK2 (0.35) | ALDH1A1PARP1MAPTKDM4EAURKA | |
| SCHEMBL11547934 | 0.70 | LMNA (0.34) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL11546538 | 0.69 | LMNA (0.33) | ALDH1A1MAPTPOLB | |
| SCHEMBL11549663 | 0.67 | CA12 (0.45) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11573902 | 0.67 | CRHBP (0.36) | GAAMAPTSMN1; SMN2RPS6KB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |