Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543960 | 0.82 | MAPT (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11549663 | 0.82 | CA12 (0.45) | KMT2AMEN1ALDH1A1GAANFKB1 | |
| SCHEMBL11573902 | 0.77 | CRHBP (0.36) | GAANFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL11545925 | 0.76 | PAX8 (0.44) | KMT2AMEN1ALDH1A1GAAPARP1 | |
| SCHEMBL11544998 | 0.73 | ALOX5 (0.36) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11544869 | 0.72 | ADRA1D (0.39) | ALDH1A1GAAPARP1SMN1; SMN2MAPT | |
| SCHEMBL4514092 | 0.69 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1GAAPARP1 | |
| SCHEMBL11547934 | 0.68 | LMNA (0.34) | KMT2AALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL11546538 | 0.67 | LMNA (0.33) | KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL11544979 | 0.67 | LMNA (0.34) | KMT2AMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |