Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544998 | 0.89 | ALOX5 (0.36) | LMNADPP4DPP8ALDH1A1NPSR1 | |
| SCHEMBL11549663 | 0.80 | CA12 (0.45) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11544869 | 0.78 | ADRA1D (0.39) | ALDH1A1NPSR1SYKMAPTGAA | |
| SCHEMBL11547934 | 0.76 | LMNA (0.34) | LMNAALDH1A1KMT2AMAPTJAK2 | |
| SCHEMBL11546538 | 0.75 | LMNA (0.33) | LMNAALDH1A1KMT2AMAPTJAK2 | |
| SCHEMBL11545794 | 0.75 | NEK2 (0.35) | ALDH1A1KMT2AMAPTMEN1CYP2C9 | |
| SCHEMBL5202849 | 0.72 | MAPT (0.41) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11544982 | 0.70 | TSHR (0.40) | KMT2ARAB9ACYP19A1 | |
| SCHEMBL11543960 | 0.69 | MAPT (0.38) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL25106757 | 0.68 | KDM4E (0.43) | LMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |