Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544982 | 0.80 | TSHR (0.40) | NPC1RAB9AKMT2APKMTSHR | |
| SCHEMBL11545003 | 0.79 | TSHR (0.40) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11544869 | 0.76 | ADRA1D (0.39) | PARP1NPC1RAB9AATMSMN1; SMN2 | |
| SCHEMBL11480530 | 0.76 | ADORA3 (0.39) | PARP1NPC1RAB9AATMSMN1; SMN2 | |
| SCHEMBL11545925 | 0.74 | PAX8 (0.44) | PARP1NPC1SMN1; SMN2KMT2AGAA | |
| SCHEMBL11545754 | 0.73 | TSHR (0.35) | SMN1; SMN2KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL11545682 | 0.72 | TSHR (0.36) | SMN1; SMN2ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL11545798 | 0.72 | SIRT2 (0.38) | KMT2AALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL5202849 | 0.70 | MAPT (0.41) | SMN1; SMN2KMT2AGAAALDH1A1MAPT | |
| SCHEMBL11549665 | 0.69 | MEN1 (0.43) | NPC1RAB9AATMSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |