Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 3/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545003 | 0.89 | TSHR (0.40) | TSHRKCNJ1KCNH2NPC1RAB9A | |
| SCHEMBL11544871 | 0.80 | PARP1 (0.39) | TSHRNPC1RAB9APKMKMT2A | |
| SCHEMBL11549665 | 0.80 | MEN1 (0.43) | TSHRNPC1RAB9ACA2KMT2A | |
| SCHEMBL11545754 | 0.75 | TSHR (0.35) | TSHRKMT2A | |
| SCHEMBL11545798 | 0.75 | SIRT2 (0.38) | STAT6KMT2AHDAC1 | |
| SCHEMBL11545682 | 0.74 | TSHR (0.36) | TSHRCA2 | |
| SCHEMBL11471693 | 0.72 | ADORA2A (0.40) | STAT6KCNJ1KCNH2NPC1RAB9A | |
| SCHEMBL5202849 | 0.72 | MAPT (0.41) | PKMKMT2A | |
| SCHEMBL11544979 | 0.70 | LMNA (0.34) | RAB9ACYP19A1KMT2A | |
| SCHEMBL11546972 | 0.70 | GLA (0.38) | TSHRNPC1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |