Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548610 | 0.82 | POLB (0.47) | ADRB3ADRB1ADRB2OPRM1OPRD1 | |
| SCHEMBL11549384 | 0.82 | POLB (0.47) | ADRB3MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11549162 | 0.78 | ADRB1 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL11548958 | 0.74 | POLB (0.57) | ADRB3OPRM1OPRD1OPRK1 | |
| SCHEMBL11545627 | 0.72 | KDM4E (0.53) | ADRB3MEN1KMT2AADRB1ADRB2 | |
| SCHEMBL11549323 | 0.72 | KDM4E (0.49) | ADRB3KMT2AADRB1ADRB2 | |
| SCHEMBL11545374 | 0.70 | ALDH1A1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11547011 | 0.69 | POLB (0.42) | ADRB3MEN1KMT2AADRB1ADRB2 | |
| SCHEMBL21759058 | 0.69 | POLB (0.59) | ADRB3MEN1KMT2AADRB1ADRB2 | |
| SCHEMBL11236059 | 0.68 | MEN1 (0.50) | MEN1KMT2AADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |