Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372476 | 0.86 | LMNA (0.42) | POLBCYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9243026 | 0.85 | CASP3 (0.56) | MAPTPOLBCASP3SENP7GAA | |
| SCHEMBL11546145 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1PTGS2HPGD | |
| SCHEMBL11546205 | 0.77 | RAB9A (0.43) | POLBGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11543446 | 0.77 | ALDH1A1 (0.47) | MAPTPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11150730 | 0.77 | ALDH1A1 (0.36) | MAPTPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6819624 | 0.75 | NAPRT (0.61) | MAPTPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11550075 | 0.75 | TDP1 (0.40) | MAPTPOLBGAACYP1A2CYP2C9 | |
| SCHEMBL11077875 | 0.74 | HDAC3 (0.30) | — | |
| SCHEMBL4053439 | 0.74 | MAPT (0.44) | MAPTPOLBGAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |