Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372476 | 0.89 | LMNA (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11545872 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8905438 | 0.80 | ROCK2 (0.60) | MAPTSMN1; SMN2ROCK2HDAC6PNPLA2 | |
| SCHEMBL11150730 | 0.79 | ALDH1A1 (0.36) | MAPTSMN1; SMN2ROCK2NPC1ALDH1A1 | |
| SCHEMBL11543446 | 0.79 | ALDH1A1 (0.47) | MAPTSMN1; SMN2HDAC1HDAC2HDAC6 | |
| SCHEMBL11546205 | 0.79 | RAB9A (0.43) | SMN1; SMN2HDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL5412087 | 0.78 | DHODH (0.40) | MAPTSMN1; SMN2HDAC1HDAC2HDAC6 | |
| SCHEMBL11550075 | 0.78 | TDP1 (0.40) | MAPTSMN1; SMN2ROCK2HDAC1HDAC2 | |
| SCHEMBL4053439 | 0.76 | MAPT (0.44) | MAPTSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL8906338 | 0.76 | MEN1 (0.57) | MAPTSMN1; SMN2ROCK2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |