Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150730 | 0.84 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TSHRPOLBGAA | |
| SCHEMBL11543446 | 0.84 | ALDH1A1 (0.47) | RAB9AALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11550075 | 0.82 | TDP1 (0.40) | RAB9AALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11372476 | 0.82 | LMNA (0.42) | RAB9AALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11373630 | 0.81 | TDP1 (0.52) | RAB9AALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL4053439 | 0.81 | MAPT (0.44) | RAB9ASMN1; SMN2TSHRPOLBGAA | |
| SCHEMBL11546145 | 0.79 | MAPT (0.41) | RAB9AALDH1A1SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL5814273 | 0.78 | ROCK2 (0.53) | RAB9AMMP13ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11545872 | 0.77 | MAPT (0.47) | RAB9AALDH1A1SMN1; SMN2TSHRPOLB | |
| SCHEMBL11798977 | 0.77 | RAB9A (0.53) | RAB9AMMP13ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |