Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454751 | 0.96 | OPRD1 (0.43) | OPRD1CNR2SIGMAR1OPRM1KDM4E | |
| SCHEMBL11347007 | 0.86 | SIGMAR1 (0.43) | OPRD1CNR2SIGMAR1OPRM1KDM4E | |
| SCHEMBL11546724 | 0.86 | MEN1 (0.40) | CNR2SIGMAR1KDM4EMEN1NPC1 | |
| SCHEMBL11447020 | 0.82 | OPRD1 (0.42) | OPRD1CNR2SIGMAR1OPRM1KDM4E | |
| SCHEMBL11454719 | 0.82 | MEN1 (0.38) | OPRD1CNR2SIGMAR1KDM4EMEN1 | |
| SCHEMBL11348032 | 0.81 | SIGMAR1 (0.59) | OPRD1SIGMAR1OPRM1MEN1ALDH1A1 | |
| SCHEMBL11472080 | 0.78 | LMNA (0.38) | CNR2SIGMAR1KDM4EMEN1NPC1 | |
| SCHEMBL11550476 | 0.77 | RAB9A (0.39) | CNR2OPRM1KDM4EMEN1NPC1 | |
| SCHEMBL11447524 | 0.77 | SIGMAR1 (0.57) | OPRD1SIGMAR1OPRM1MEN1ALDH1A1 | |
| SCHEMBL11549687 | 0.76 | OPRM1 (0.49) | OPRD1SIGMAR1OPRM1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |