Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461047 | 0.83 | POLB (0.59) | ALDH1A1KMT2AMEN1POLBCYP1A2 | |
| SCHEMBL31163274 | 0.83 | POLB (0.59) | ALDH1A1KMT2AMEN1POLBCYP1A2 | |
| SCHEMBL10548910 | 0.81 | CTSD (0.58) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL1336721 | 0.77 | LMNA (0.42) | ALDH1A1KMT2AMEN1CYP3A4SMN1; SMN2 | |
| SCHEMBL9130555 | 0.76 | SLC6A4 (0.67) | SIRT1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4461923 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1POLBCYP1A2 | |
| SCHEMBL29530768 | 0.76 | SIRT1 (0.64) | SIRT1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL3077375 | 0.76 | SIRT1 (0.77) | SIRT1ALDH1A1POLBCYP3A4CYP2C19 | |
| SCHEMBL11821622 | 0.76 | SIRT1 (0.64) | SIRT1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL1399456 | 0.76 | SIRT1 (0.64) | SIRT1ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116966177-A | Combined medicine containing nifuratel acid amide derivative and application thereof | 成都贝诺科成生物科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116966177-A | Combined medicine containing nifuratel acid amide derivative and application thereof | 成都贝诺科成生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116966177-A | Combined medicine containing nifuratel acid amide derivative and application thereof | 成都贝诺科成生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-4152518-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4152518-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4112105-A | Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4112105-A | Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |