Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163274 | 1.00 | POLB (0.59) | POLBCA12CA1CA2CA4 | |
| SCHEMBL11554587 | 0.83 | SIRT1 (0.53) | POLBALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10548910 | 0.79 | CTSD (0.58) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL1336721 | 0.79 | LMNA (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2762223 | 0.79 | MAPT (0.40) | POLBCA12CA1CA2CA4 | |
| SCHEMBL3273024 | 0.77 | CA12 (0.48) | POLBCA12CA1CA2CA7 | |
| SCHEMBL2028311 | 0.75 | SLC6A2 (0.68) | POLBCA12CA1CA2CA4 | |
| SCHEMBL144989 | 0.74 | POLB (1.00) | POLBCA12CA1CA2CA4 | |
| SCHEMBL1482567 | 0.74 | POLB (0.74) | POLBCA12CA1CA2CA4 | |
| Phthalic Acid SCHEMBL16280460 | 0.74 | ALDH1A1 (0.70) | POLBCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118750602-A | Magnesium molten iron talcum-based nanocomposite and preparation method and application thereof | 衢州资源化工创新研究院 | 2024-10-11 | — | — | CN | disclosed |
| CN-107849121-B | Blocked and unblocked antibody cysteines and their use in antibody-drug conjugation | 辉瑞公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-109985061-B | Application of dendrobe polysaccharide in preparation of medicine for preventing and/or treating prostatic hyperplasia | 暨南大学 | 2021-07-27 | — | — | CN | disclosed |
| EP-1739188-B1 | METHOD OF MEASURING ACTIVITY OF HOMOCYSTEINE THIOLACTONE HYDROLASE | ALFRESA PHARMA CORP (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-7534581-B2 | Method for measurement of activity of homocysteinethiolactone hydrolyzing enzyme | ALFRESA PHARMA CORPORATION (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20070243571-A1 | Method for Measurement of Activity of Homocysteinethiolactone Hydrolyzing Enzyme | ALFRESA PHARMA CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1739188-A1 | METHOD OF MEASURING ACTIVITY OF HOMOCYSTEINE THIOLACTONE HYDROLASE | Alfresa Pharma Corporation (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-5208158-A | Cleaning compounds | NOVO NORDISK A/S (DK) | 1993-05-04 | — | — | US | disclosed |